Sulfasalazine Side Effects

...less medical jargon in a 'Quick Glance' format!

If you have sulfasalazine side effects, tell your doctor if any of these symptoms are severe or do not go away:

  • diarrhea
  • headache
  • loss of appetite
  • upset stomach
  • vomiting
  • stomach pain
If you have any of the following symptoms, stop taking sulfasalazine and call your doctor immediately:
  • skin rash
  • itching
  • hives
  • swelling
  • sore throat
  • fever
  • joint or muscle aches
  • pale or yellow skin
  • difficulty swallowing
  • tiredness
  • unusual bleeding or bruising
  • weakness

Sulfasalazine (brand name Azulfidine) is a sulfa drug, a derivative of Mesalazine, used primarily as an anti-inflammatory agent in the treatment of inflammatory bowel disease as well as for rheumatoid arthritis. It may be abbeviated SSZ. It is not a pain killer.

It has been found to reverse the scarring associated with cirrhosis of the liver. Apparently, cells called myofibroblasts, that cause scar tissue to form in a diseased liver, also give off proteins that prevent the breakdown of the scar tissue. Sulfasalazine appears to retard the secretion of these proteins.


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...less medical jargon in a 'Quick Glance' format!